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Bone Physiology and Wound Healing
The events involved in osseous wound healing around implants recapitulate the events of wound healing which is depicted in the flowchart.
The effect of many inflammatory mediators, eicosanoids, interleukins and is it chemokines on bone formation and osteoblast behaviour in culture strongly implicates the implication of post surgical inflammatory processes in determination of bone formation.
After the establishment of a well vascularised, immature connective tissue, osteogenesis continues by the recruitment, proliferation and differentiation of the osteoblastic cells. Differentiated osteoblast secretes a collagenous matrix and contributes to its mineralization.
Eventually during the formation, the matrix surrounds the osteoblastic cells and mineralization of a collagenous rich matrix is completed. This cell rich and unorganized bone is called woven bone. The transformation of woven bone to lamellar bone i.e. bone organized to resist physical strain and displaying a haversian architecture, is another important part of osseointegration. Thus, osseointegration involves the direct bone apposition on the implant surface followed by the structural adaptation of the bone to mechanical load and represents a lifelong process of bone formation, adaptation to function and repair of bone
Q. Explain Use of Toxic amino acids? Lathyrus sativus (kesari dhal) seeds contain toxic amino acid beta-oxalyl aminoalanine (BOAA), is considered to be responsible
Occlusal load affect Osseointegration The timing and amount of overload are critical for osseointegration. Occlusal loading early, where the primary stability is low leads to h
Explain the Food Security? You were introduced to the concept of food security in Unit 2. Food security, we learnt, is access by all people at all times to enough food for an a
Osmoregulation in Non-Chordate Metazoans Previously you have studied that in protozoans, particularly fresh water protozoans; contractile vacuoles play a significant role in t
Explain the OBJECTIVES of history of mart disease? After reading this unit, you should be able to: 1. Understand the importance of Cardio-vascular diseases as the leading cause
Question 1) What is megalobastic anemia? Discuss briefly its lab diagnosis. How would you differentiate megaloblastic anemia from other anemias? Question 2) What is hem
Defence mechanisms of the host The healthy animal is protected from pathogenic organisms present in the environment by virtue of the effective immune mechanism present from bi
Cilia and Flagella – Protozoans Cilia and flagella basically have a similar structure and distinction between the two on structural basis does not exist. There is a filament o
Nutritional and functional role of minerals in foods Essential elements including the main elements and a number of trace elements fulfill various functions: as electrolytes, a
Simple interrupted technique of Suturing The simple loop is the most commonly used technique in dentistry and is routinely used to adapt tension free, mobile surgical flaps.
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