Q. Drug Management for gout disease?

Drugs are so effective in lowering the serum mate concentration that rigid restriction of dietary purines is rarely necessary. Uricosurie drugs are used to increase uric acid excretion; Allopurinol inhibits the action of enzyme xanthine oxidase, which then. Produces less uric acid. These drugs must be taken close to the meals as prolonged use could damage the intestinal mucosa resulting in reduced absorption of several nutrients and large quantities of water. The person will lose weight gradually and must avoid excessive intake of alcohol.

The inborn errors of metabolism, which you may recall reading earlier in this unit, are inherited traits that result in the absence or reduced activity of a specific enzyme or a co-factor.