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In eukaryotes possibly the most rapid and complex signaling is mediated through nerve impulses. The Nerve cells (neurons) consist of a cell body with numerous projections of the plasma membrane, called as dendrites. These interact with other cells and receive information from them in the form of nerve impulses. Cell body then assimilates the information derived from a number of dendritric contacts and passes on the information as another nerve impulse down the huge axon. The axon ends at the synapse where it makes contact with the post-synaptic (target) cell. The axon is covered in places by a membranous myelin sheath, made up commonly of the lipid sphingomyelin, that acts as an electrical insulator and enabling the nerve impulses to be trnasferred over long distances sometimes more than 1 m in larger animals.
figure: Schematic diagram of a typical nerve cell.
IS Neuron B in the frog central nervous system Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectly cond
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