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Describe Intemittent Mandatory Ventilation (IMV)
Mandatory breaths are delivered at set tidal volumes and rates, and the patient can breathe on his own in between through a unidirectional valve in between (Fig 5). Unlike in ACV, a machine breath is not initated with each patient effort - thus the risk of overventilation is reduced. A refinement of this mode is Synchronous Intermittent Mandatory Ventilation (SIMV) - here the machine breaths are synchronized to patient efforts if it falls within a "window period" of the cycle.
Figure: The IMV Circuit
Nuclease is an enzyme which degrades the nucleic acids. A nuclease can be DNA-specific (a DNase), RNA-specific (RNase) or non-specific. It might act only on single stranded nuclei
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