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Define Vitamins B12 Deficiency in Vegans?
Because plants do not synthesize vitamin B12, individuals who consume diets completely free of animal products (vegan diets) are at risk of vitamin B12 deficiency. This is not true of lacto-ovo vegetarians, who consume the vitamin through eggs, milk and other dairy products.
Persons living exclusively on vegetarian diets (vegans) have low serum levels of vitamin B12 and develop specific symptoms such as sore tongue, paraesthesia and signs of degeneration of the long tracts of the spinal cord as a result of low intakes of vitamin B12. Megaloblastic anaemia is not so common when folic acid intake is adequate. The anaemia results from decreased DNA synthesis and failure of the cells to divide properly, coupled with the continued formation of RNA.
In animals, some of bacteria and fungi, and the first step in tetrapyrrole synthesis is the condensation of the amino acid glycine with succinyl CoA (an intermediate of the citri
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