Define the term- brain circuitry underlying addiction

By unraveling brain circuitry underlying addiction, scientists have identified new targets for therapies which might quell the compulsion to use drugs or ease withdrawal. Continuing research in this area is a crucial public health goal: substance abuse has wide ranging consequences for communities, families, and society at large, directly affecting an estimated 22 million Americans and carrying an economic price tag of more than $245 billion yearly, according to government estimates.