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A complete motor neuron is removed from a frog and placed in a large volume of normal physiological saline. The neuron is healthy; it has a stable resting voltage of -70 millivolts.
It is not producing any action potentials; its threshold for an action potential is -50 millivolts. The only ligand-gated Receptors in the neuron's plasma membrane are AMPA Receptors, GABAB Receptors, and glycine Receptors. The equilibrium potential for chloride ions is -70 millivolts, the equilibrium potential for potassium ions is -90 millivolts, and the equilibrium potential for sodium ions is +60 millivolts.
A. The addition of glycine to the physiological saline will lead to no change in the amount of intracellular chloride.
B. The addition of glycine and GABA to the physiological saline will lead to a decrease in the amount of intracellular chloride.
C. The addition of glycine and glutamate to the physiological saline will lead to a decrease in the amount of intracellular chloride.
A new drug named AGON-CaSR has been developed that is an agonist at calcium-binding sites of CaSRs (Calcium-Sensing Receptors) in plasma membranes of parathyroid gland cells.
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