Define the blood coagulation - function of vitamin k, Biology

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Define the Blood coagulation - Function of Vitamin K?

The primary function of vitamin K in the body is in the maintenance of normal blood coagulation. The vitamin K-dependent coagulation  proteins are synthesized in the liver and comprise Factor IT (prothrombin), Factor  VII (proconvertin), Factor IX (Christmas factor) and Factor X (Stuart factor),  which have a haemostatic role i.e. they are procoagulants that arrest and prevent  bleeding.

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Let us get to know how this mechanism works. Prothrombin is converted to its active form, thrombin, which in turn, is necessary for the formation of fibrin, a protein that is the basis for a blood clot, as shown in Figure. Vitamin K also acts as a cofactor for an enzyme in the liver which converts glutamic acid residues in a precursor process to gamma - carboxy glutamic acid. This reaction is necessary before prothrombin can function in blood coagulation.


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