Define role of polyunsaturated fatty acids - gene expression, Biology

Assignment Help:

Define Role of polyunsaturated fatty acids - Gene Expression?

In contrast, polyunsaturated fatty acids (PUFA) inhibit G6PD in both intact animals and in primary hepatocytes in culture. The inhibition occurs in rats switched from a high-carbohydrate fat-free diet to one with PUFA and when starved rats are re-fed a high-carbohydrate diet supplemented with PUFA. Addition of saturated fatty acids or monounsaturated fatty acids does not inhibit G6PD activity. The inhibitory effect of PLFA is unique to G6PD activity in the liver. PUFA in the diet do not affect the enzyme activity in the adipose tissue.

The available evidence suggests that the regulation of G6PD gene expression by nutritional and hormonal factors occurs at the post-transcriptional step. The abundance of G6PD RNA appears to be regulated during the processing of the nascent transcript, Steps  that involve either splicing or polyadenylation of the pre-mRNA. Re-feeding enhances the efficiency of splicing and increase polyadenylation.


Related Discussions:- Define role of polyunsaturated fatty acids - gene expression

Endocrine glands - heart, HEAR T - The cells called cardiocytes of atr...

HEAR T - The cells called cardiocytes of atria of the heart secrete peptide hormone called atrial natriuretic factor (ANF) in response of an increased return of the deoxygen

What is mass transportation across the cell membrane, What is mass transpor...

What is mass transportation across the cell membrane? Mass transportation is the entrance or the exiting of substances in or from the cell engulfed by portions of membrane. The

What compound composes most of the cell membrane, What compound composes mo...

What compound composes most of the cell membrane? How is this compound suited to the function of the membrane? Phospholipid composes most of the cell membrane. The hydrophob

Explain proteins as lubricants, Explain Proteins as lubricants? The muc...

Explain Proteins as lubricants? The mucous of the respiratory tract, oral cavity, vaginal tract and the rectal cavity reduces the irritation which might be caused by materials

Taxonomy, what is the taxonomic classification for the protist Archaeplasti...

what is the taxonomic classification for the protist Archaeplastida?

Poultry and duck diseases-avian reovirus infections, Avian reovirus infecti...

Avian reovirus infections There are several avian reoviuses isolated from chicken, turkey and other species of birds. They are associated with arthritis (tenosynovitis), respir

Olericulture, Olericulture: It concerned with the cultivation or developme...

Olericulture: It concerned with the cultivation or development of vegetables yielding plants. Olericulture is the study of vegetable growing, dealing with the culture of non-woody

Guidelines for diagnosis and treatment planning, Guidelines for diagnosis a...

Guidelines for diagnosis and treatment planning The diagnosis and planning the case is by far the most important step in the entire sequence of the treatment and due considerat

Potassium ions maintain the resting potential of neuron, Q. How do the pota...

Q. How do the potassium and sodium ions maintain the resting potential of the neuron? The plasma membrane of the neuron when at rest maintains an electric potential difference

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd