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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
Q. Define X-Ray Chest and Coronary Angiography? X-Ray Chest It shows cardiomegaly with left ventricle (LV) and left atrium (LA) enlargement. There may be signs of pulmona
What is the meaning of Ideometric approach Ideometric approach in the context of neuropsychological assessment emphasises the patient's premorbid functioning with reference to
Q. What are active and passive immunization? According to the duration of the protection how do these types of immunization differ? Active immunization is that in which an anti
Cortex can be described as follows 1) The outer part of the organ, such as, the adrenal cortex, which produces many steroidhormones; 2) in plants, the area of the stem or root
Locomotion,nutrition and reproduction in ptotozoa
If you look up a world atlas you would notice that most of the earth's surface is covered by the waters of the oceans (about 71%). Beneath the water surface is a fascinating world
How many ATP molecules are made after glycolysis? Glycolysis is a process same to glucose degradation in fermentation. It forms (final balance) two molecules of ATP for each br
What are the four types of weak bonds, and how do they differ from each other and from covalent bonds? When you eat a salad with lettuce, croutons, hard-boiled egg, bacon bits,
Describe TR Murmur and VSD murmur in details? TR Murmur : Characteristic: Holosystolic murmur, loudest at left lower-sternal border and becomes louder with inspiration (Carv
Gastrulation Process - Formation of Primitive Streak Gastrulation in all amniotes involving eutherian mammals is related to a characteristic structure termed as the primitive
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