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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
State the term - Aneurysms Aneurysms are vascular dilations resulting from localised defects in the elasticity of a vessel. They can be visualised as balloon like expansions of
Hypertensive emergencies are one of the important categories of hypertension and characterized by severe elevations in BP that are complicated by evidence of progressive target org
The first step should be to determine the status of dehydration. We have already talked about the mild, inoderate and severe dehydration. In mild to moderate cases fluid, electroly
Addition of glycine to the physiological saline A complete motor neuron is removed from a frog and placed in a large volume of normal physiological saline. The neuron is heal
Determine Some indicators of Malnutrition? A few of the indicators are enumerated below: 1. Indicators related to Government policies a. Nutrition policy b. Nutrition
Determine the Adequacy of children's food? Adequacy of children's food and nutrient intake depends on: Sibling company Peer pressure Model set by parents and
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How to culture mould plant s Use either sterile dishes with potato slices or gelatin as those ready for the experiments on bacteria. Transfer mould from every of the sources in
Which is the kind of gamete produced by a heterozygous individual? And what is the genotypical proportion of these gametes? The Heterozygous individuals, for instance, AA, prod
Q. Define Stress Echocardiography with Adenosine? These have all been described. The information is that of wall motion abnormality indicating ischaemia. Ejection fraction can
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