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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
Going south of taiga you would reach the temperate regions of the planet. These regions experience moderate temperatures on average that change during four distinct seasons. They h
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what is the life cycle of plasmodium vivax?
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What Devices Used for Oxygen Therapy? Variable performance systems: With these devices, the FiO 2 would vary depending on the patient's breathing pattern. In general, rapid, s
HOW BORN THE BABY
Question 1 How would you perform ABO blood grouping? Add a note on advantages and disadvantages of each method. Also discuss the precautions you may take to avoid errors in variou
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