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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
Q. Show Imbalances of basal nuclei? BASAL NUCLEI - Gray matter "islands" located deep within cerebral white matter. These nuclei process a variety of descending motor informat
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The three charges in the figure below are at the vertices of an isosceles triangle. Let q = 7.00 nC and calculate the electric potential at the midpoint of the base.
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What are the physical propertie of sol Sols resemble liquids in their main physical properties - that is, they flow and they do not show rigidity of form. However, when a sol a
Assuming that the equilibrium potential for sodium ion across a skeletal muscle is +66 mv at a temperature of 37 degree celcius when the external concentration is 145 mM and the in
What are chylomicrons? Yes, so you now know that chylomicrons are basically lipoprotein molecules which are water miscible. They are poured into lymphatic vessels through lacte
Hepaticae (Liverworts) The gametophyte is thalloid body or simple stem and leaves, with aquatic or semi-terrestrial habit. Rhizoids are multiceillular. Some examples : Mar
human digestive system and the functions
Adenosine triphosphate (ATP) is a general form in which the energy is stored in living systems; comprises of a nucleotide (with ribose sugar) with three phosphate groups. Energy c
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