Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

Explain working of refrigerator in microbiology laboratory, Explain the Wor...

Explain the Working of Refrigerator in Microbiological Laboratory? Refrigerator is a basic requirement in microbiological laboratory. It is used for maintaining microbial cultu

To study if bacteria grow better where it is warm or cold, To study if bact...

To study if bacteria grow better where it is warm or cold Again inoculate two sterile dishes. Label one 'warm'  and the other 'cold'. Place the 1st dish in a dark warm place an

Chromosome walking, Chromosome walking is the technique for cloning everyt...

Chromosome walking is the technique for cloning everything in genome around the known piece of DNA (the begning probe). You screen the genomic library for all the clones hybridizi

Explain main functions of organic molecules for living being, What are the ...

What are the major functions of the organic molecules for living beings? Organic molecules, such as proteins, lipids and carbohydrates, perform numerous functions for living or

How is the body of gastropods divided, How is the body of gastropods divide...

How is the body of gastropods divided? The body of gastropods is separated into three main portions: a) Head, b) The visceral mass and c) Foot.

What are the healing events around implants, Healing Events around Implants...

Healing Events around Implants Healing of an implant is compared with the processes in normal bone healing or bone regeneration and with stable osteosynthesis.

Explain indications for surgery of total anomalous, Explain Indications for...

Explain Indications for Surgery of Total Anomalous pulmonary Venous Connection ? Once TAPVC is diagnosed in a neonate with symptoms, operation should be undertaken immediately.

Phylum annelida, what so special for phylum annelida

what so special for phylum annelida

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd