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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
Functional regions of digestive system In general the digestive system of metazoans is divided into 4 major functional regions of: Reception Conduction and s
Q. What is Dietary fibre? Dietary fibre is defined as plant polysaccharide resistant to hydrolysis by the digestive enzymes in the human intestinal tract. It includes: • Str
Define lipids 'lipids' defines substances as oils, fats and waxes which can be only characterized by a large array of properties. They are in general: - coming from plant
Define Goals of National and International Requirement Estimates and RDAs? One of the goals of the RDAs has been reiterated through this unit. They serve as the guidelines for
Senescence Plants begin their development after seed germination. They grow, flower and finally senesce and die. The period from the start to death is called the longevity or
What is global warming? Global warming is the enhance in the temperature of the planet due to accumulation of some gases in the atmosphere, especially gases that retain the sol
M-Mode was the earliest form of cardiac ultrasound used clinically. It displays the amplitude signals of various structures along the length of ultrasound beam with distance or
What is the difference between extra. and intraradicular? Extraradicular means there is lesions came from periodontal or from the adjacent tissue and make periapical infection
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Define Protein needs in Nutrient Requirement and Dietary Management? It is one of the most crucial nutrient which determines the ultimate outcome of burns. Amino acid requireme
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