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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
In his experiments, Mendel noted that when two traits are involved in a genetic cross, they are inherited independently of each other. The reason for this is that A. genes on the s
Explain the term Rastelli operations ? This is the operation of choice for transposition with VSD and left ventricular outflow obstruction. The principle of this operation is:
Explain the Procedure for Preparation of General Purpose Media Procedure: Now prepare the media following the steps enumerated herewith: 1. Weigh and dissolve each ingredien
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Topology and Cell Organ Shapes Topology is an abstract mathematical exercise that deals with the possible shapes and surfaces of an endlessly/infinitely elastic body. Most cel
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Explain the Regulation of blood pressure? The renin-angiotensin system regulates the blood pressure. The synthesis of renin is decreased by calcitriol through its interaction
Explain the term- Latent Squint (Anisophoria or Heterophoria) This eye condition occurs when the balance of extra-ocular muscles is altered. There is a tendency of the eye to
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