Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

How the rhizopus reproduce?, How the Rhizopus reproduce? Rhizopus usual...

How the Rhizopus reproduce? Rhizopus usually reproduce asexually, but under unfavourable conditions, sexual reproduction (isogamous) occur resulting in formation of zygospores

What are the three main types of passive transport, What are the three main...

What are the three main types of passive transport? The three main kinds of passive transport are a)  simple diffusion, b)  osmosis and c)  Facilitated diffusion. C

Explain about the term - paediatric neuropsychologist, Explain about the te...

Explain about the term - paediatric neuropsychologist In the evaluation of infants and young children, all sources of reliable and valid data available to the paediatric neurop

Explain epididymitis, Epididymitis  Acute epididymitis in men less than...

Epididymitis  Acute epididymitis in men less than 35 years old is usually caused by C. trachomatis or, less frequently, N. gonorrhoeae. Older men or those who have had urinary

Psychedelic drugs (hallucinogens), PSYCHEDELI C DRUGS (HALLUCINOGENS) - ...

PSYCHEDELI C DRUGS (HALLUCINOGENS) - They act mainly on CNS and greatly alter one's thoughts, feelings and perceptions, called psychedelic drugs. They cause optical or a

Do all mammals have a placenta, Q. Do all mammals have a placenta? Mamm...

Q. Do all mammals have a placenta? Mammals of the monotreme group (platypus, echidnas) are oviparous egg- laying and they don't have a placenta. Mammals of the marsupial group

Evolution, write similaritie between the two species?

write similaritie between the two species?

What are the symptoms of brown-sequard syndrome, What are the Symptoms of B...

What are the Symptoms of Brown-Sequard syndrome Symptoms of Brown-Sequard syndrome usually appear after an affected individual experiences a trauma to the neck or back. First s

What phenotypic ratios of the diploid, A wild-type strain of haploid yeast ...

A wild-type strain of haploid yeast is crossed to a mutant haploid strain to make a diploid. What phenotypic ratios will be observed in the haploid progeny of the diploid?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd