Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

What are the two reactants, what are the two reactants and the two products...

what are the two reactants and the two products of a dehydration reaction/ What are the two reactants and products of a hydrolysis reaction

Where can rna be found within cells, Where can RNA be found within cells? ...

Where can RNA be found within cells? In the eukaryote cell nucleus RNA can be found dispersed in the nuclear fluid, with DNA, and as the main constituent of the nucleolus. In c

Benefits of haccp, The benefits of HACCP  can be  summarized  as under. ...

The benefits of HACCP  can be  summarized  as under. a)  Benefits to Consumers Reduced risk of food borne diseases Increased confidence in food supply Increased awar

What is the difference between taeniasis and cysticercosis, Q. What is the ...

Q. What is the difference between taeniasis and cysticercosis? The Taeniasis is the parasitic disease caused by the adult tapeworm installed within the human intestine. The

Explain the treatment of lyme disease, Treatment of Lyme Disease Lyme d...

Treatment of Lyme Disease Lyme disease in North America is caused by the spirochete  Borrelia burgdorferi, which is transmitted to humans by Ixodes scapularis or pacificus tick

Physiological adaptation of parasites for infectioness, physiological adapt...

physiological adaptation of parasites for infectiousness?

Total darkness and pea seedlings grown in the light, What differences would...

What differences would you expect to see among pea seedlings grown for 10 days in total darkness and pea seedlings grown in the light for the similar period of time?   The s

Obtain half their genes from one parent, If children obtain half their gene...

If children obtain half their genes from one parent and half from the other parent, why aren't siblings identical?

Genotype for each individual, The allele that causes albinism (p) is recess...

The allele that causes albinism (p) is recessive to the allele for normal pigmentation (P). A normal woman whose father is an albino marries an albino man whose parents are both no

What is leaf morphology, What is Leaf Morphology? Leaf Arrangemen...

What is Leaf Morphology? Leaf Arrangement : These show the different types of leaf arrangement on a twig. The point on the twig at which the leaves are attached is refer

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd