Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

Use of masks as personal protective equipment, Q. Use of Masks as personal ...

Q. Use of Masks as personal protective equipment? Masks are to be worn when procedures that result in aerosol production are performed. Protection from these masks only affords

What are some fungal diseases transmitted by animal feces, What are some fu...

What are some fungal diseases transmitted by animal feces? Bat and pigeon feces can carry Histoplasma capsulatum, the fungus agent of histoplasmosis. The infection is transmitt

Explain nsp and food hydrocolloids, NSP NSP or dietary fibre is the nam...

NSP NSP or dietary fibre is the name given to a group of materials found in the cell walls of plants which gives the plant its structure and form. Food hydrocolloids Fo

Explain epididymitis, Epididymitis  Acute epididymitis in men less than...

Epididymitis  Acute epididymitis in men less than 35 years old is usually caused by C. trachomatis or, less frequently, N. gonorrhoeae. Older men or those who have had urinary

Uses of urine, Uses of Urine Urine is natural, easily available, harmle...

Uses of Urine Urine is natural, easily available, harmless, beneficial compound, which offers protection against a number of diseases. Now a day's urine after distillation from

Severity of heat treatment for pasteurization depends on, Define on which s...

Define on which severity of heat treatment for pasteurization depends? The severity of heat treatment for pasteurization depends on: 1.  Heat resistance of target microorgan

Dreams, what do our brain and heart do when we are asleep?

what do our brain and heart do when we are asleep?

Swine-pox, Swine-pox Pigs of 2 months of age may be infected with vaccinia...

Swine-pox Pigs of 2 months of age may be infected with vaccinia either naturally or artificially and show pox lesions on the eyelids, snot, inside the thigh and undersurface of th

Explain spontaneous closure of defects in details, Explain Spontaneous Clos...

Explain Spontaneous Closure of Defects in details? Some defects have a tendency towards spontaneous closure and this can influence the timing of intervention. The defects known

Animal viruses, Chart of taxonomy of animal viruses

Chart of taxonomy of animal viruses

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd