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Define Role in growth and cellular Differentiation?
The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency. In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin. Classical symptoms of xerosis (drying or non-wet ability) and desquamation of dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external evidence of the changes also occurring to various degrees in internal epithelial tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.
Andalusian chickens may be either black, white, or gray. The gene for black is not dominant over the gene for white, nor is the gene for white dominant over the gene for black. Whe
Define Interaction of Folate with Vitamin C? Vitamin C: Anaemia is observed in vitamin C deficient patients. Normochromic, normocytic or macrocytic or megaloblastic ana
A woman is heterozygous for three X-linked loci: AaBbDd. She has seven sons with the following genotypes: two are X ABd Y three are X abD Y one is X ABD Y one is X Abd
Q. What is ST depression at rest? As early as 1965 Ostrand called attention to the syndrome of short PR interval without accelerated conduction and it's association with ST dep
Oreopithecus, a late rniocene primate had very close resemblances to those of gibbons, although the tooth structure showed that the animal was only a monkey and not a hominoid. Ano
Preliminary treatment of implant therapy It is important to ensure a healthy oral environment before going ahead with implant procedure. The treatment needs to be initiated in
Q. What are the endocrine functions of the placenta? The placenta has endocrine function since it secretes the hormones estrogen and progesterone that maintain the endometrium
What are examples of nematodes? Ascaris, hookworm and filaria, all parasites of humans, are instance of nematodes (also called as roundworms).
Explain Irradiation The physical process of exposing an object, system, or a material to a high radiant energy for the sterilization or preservation.
Effects on Health - Water Pollution Water pollution deteriorates the quality of water used for drinking, bathing, swimming, recreation and irrigation. Water contaminated with
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