Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

Process of behaviour change, 1. Awareness - First people become aware of a...

1. Awareness - First people become aware of a problem. 2. Acquire Knowledge and skills - Next, they gather knowledge and learn new skills. 3. Motivation - At the next stag

Sponges, Ask qimporatance of sponge in tourism industry

Ask qimporatance of sponge in tourism industry

Interesting areas of bioinformatics, Looking at what the academic world is ...

Looking at what the academic world is publishing, microarray research is actually hot right now, and people haven't quite figured out what the best way is (some might argue if we s

What is imbibition, What is Imbibition The ability of colloids to pick ...

What is Imbibition The ability of colloids to pick up water and swell when they come in contact with water is called imbibition. Imbibition is usually accompanied by the evo

Derive gorlin formula, Q. Derive Gorlin Formula? Formula I: First Hydra...

Q. Derive Gorlin Formula? Formula I: First Hydraulic Formula (Toricelli's law) F = AVCc Where, F = flow rate A = orifice area Cc = coefficient of orifice cont

Nature and structure of community, Nature and Structure of Community E...

Nature and Structure of Community Every place on earth -grasslands, forests, and ponds, edge of the river or sea is shared by many coexisting organisms. Plants, animals and mi

Capillaries - circulation, Normal 0 false false false E...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Meaning of gestational diabetes mellitus, Q. Meaning of Gestational Diabete...

Q. Meaning of Gestational Diabetes Mellitus? In this type of diabetes, increased blood sugar level is first diagnosed or recognized during pregnancy. Women are not known as dia

Storage and distribution - sterilization process, Packs, pouches, and casse...

Packs, pouches, and cassettes are sometimes wet after completing the sterilization process. This is a problem usually associated with the use of paper or paper/ plastic wraps in t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd