Define role in growth and cellular differentiation, Biology

Assignment Help:

Define Role in growth and cellular Differentiation?

The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In addition, goblet cell numbers we reduced in epithelial tissues and as a consequence, mucous secretions diminish. Cells lining protective tissue surfaces fail to regenerate and differentiate; hence they flatten and accumulate keratin.  Classical symptoms of xerosis (drying or non-wet ability) and desquamation of  dead surface cells as seen in ocular tissue (i.e. xerophthalmia) are the external  evidence of the changes also occurring to various degrees in internal epithelial  tissues. Current understanding of the mechanism of vitamin A action within cells outside the visual cycle is that cellular functions are mediated through specific nuclear receptors. Binding with specific isomers of retinoic acid (i.e.all Tran- and 9-cis-retinoic acid) activates these receptors. Activated receptors bind to DNA response elements located upstream of specific genes to regulate the level of expression of those genes. These retinoid-activated genes regulate the synthesis of a large number of proteins vital to maintaining normal physiologic functions. There may, however be other mechanisms of action that are as yet undiscovered.

 


Related Discussions:- Define role in growth and cellular differentiation

Which organs form the human respiratory system, Q. What are the organs that...

Q. What are the organs that form the human respiratory system? The organs that are part of the human respiratory system can be divided into three groups: lungs, respiratory mus

Define the role of vitamin d in the immune system, Define the Role of Vitam...

Define the Role of Vitamin D in the immune system? Immune responses that are, mediated by T-cells can be inhibited by tile large doses of calcitriol i.e. 1, 25 dihydroxycholec

Properties of receptors, Properties of Receptors The receptors collect...

Properties of Receptors The receptors collect information concerning the change in the environment such as temperature, illumination etc. In lower animals, sensory perception

What is prophylaxis, What is prophylaxis? Prophylaxis are measures take...

What is prophylaxis? Prophylaxis are measures taken to stop diseases. For instance, the use of condoms in sexual relations is a prophylaxis against contamination by agents that

Obelia, whyis it considered to showintermideate grade oforganisation

whyis it considered to showintermideate grade oforganisation

Drowning - paediatric emergencies, Drowning: Drowning is a cause of a...

Drowning: Drowning is a cause of accidental death  in children Accidental drowning may occur because children  do not  have adequate protective supervision.  It may be defined

Explain some features of aspergillus, Explain some Features of Aspergillus?...

Explain some Features of Aspergillus? The identifying features include: 1. Macroscopically Aspergillus colonies are powdery and are of different colours like green, blue, bl

What is gastrulation, Q. What is gastrulation? How during gastrulation are ...

Q. What is gastrulation? How during gastrulation are the first two germ layers formed? What are these germ layers? Gastrulation is the process through which a portion of the bl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd