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The formation of surface blebs caused by ischemia reflects in part plasma membrane injury, but also a sign of cytoplasmic injury. Which filamentous component of the cytoplasm plays the most important pathogenetic role in the formation of these blebs?
peroxisomes
phospholipids
cytoskeleton
mitochondria
endoplasmic reticulum
As heart failure sets in, there is activation of RAS (Fig 2.1). Adrenergic stimulation of beta-1 receptors in juxtaglomerular apparatus of the kidneys results in release of renin.
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