Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Explain restriction endonucleases are enzymes, Restriction endonucleases ar...

Restriction endonucleases are enzymes which: 1. make cuts at specific positions within the DNA molecule 2. recognize a specific nucleotide sequence for binding of DNA ligase

Psychology, Psychology : This is the study of human mind. On other words Ps...

Psychology : This is the study of human mind. On other words Psychology is the science of behavior or mental processes. Its immediate aim is to understand the individuals or groups

Which are the phases of the menstrual cycle, Q. Which are the phases of the...

Q. Which are the phases of the menstrual cycle? The menstrual cycle is divided into two major phases: the luteal (or secretory) phase and the follicular (or menstrual) phase.

Mineral nutrition, Normal 0 false false false EN-IN X...

Normal 0 false false false EN-IN X-NONE X-NONE

Explain astrand cycle test, Explain Astrand Cycle Test? This is a sub m...

Explain Astrand Cycle Test? This is a sub maximal test done on cycle ergo meter. In this test, comparatively lower wattages are set. For example, for males less than 35 years o

Cloning of arg3 gene, 1)  You want to clone the arg3 gene, which encodes an...

1)  You want to clone the arg3 gene, which encodes an enzyme in the arginine biosynthetic pathway in Neurospora crassa.  You have available the E. coli plasmid vector shown in part

Determine about the halstead''s method, Determine about the Halstead's meth...

Determine about the Halstead's method Reitan adopted Halstead's methods and various test procedures and with them established a laboratory at the University of Indiana. He supp

Determine the sarcomere of a skeletal muscle, In the sarcomere of a skeleta...

In the sarcomere of a skeletal muscle, there are A. myosin molecules in the I band. B. both tropomyosin and myosin molecules in the region of the A band that is not in the H

Science in the ancient world, Science in the ancient  world: We have e...

Science in the ancient  world: We have explained why we should study the history of science and what we mean by the history of science. We have seen what science is like in t

Agro industrial-zinc, Zinc Zinc regulates over a dozen important enzym...

Zinc Zinc regulates over a dozen important enzyme systems involved in metabolism of protein and carbohydrates. Zinc is also required for maintaining responsiveness of the immu

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd