Clotting mechanism, Biology

Assignment Help:

Clotting Mechanism

Four substances are necessary for coagulation of blood; prothrombin, thromboplastin, calcium and fibrinogen. Prothrombin gives rise to thrombin, an enzyme. Fibrinogen, prothrombin, and calcium are present in circulating blood. Thromboplastin (a lipid or fat-like compound containing phosphorus) is widely distributed throughout the tissues, the lung and brain being especially rich in this factor. It is absent or present in only small quantities in blood plasma. When blood is shed, thromboplastin is liberated from injured tissue and probably also from the leucocytes of the blood itself. The thromboplastin, acting upon the prothrombin in the presence of calcium in an ionised form, converts, it to active thrombin. Thrombin acts in turn upon the inactive fibrinogen, converting it into insoluble fibrin which is deposited as fine threads to form the framework of the clot. In simplest possible terms the chief factors are summarised in the following scheme:

 

248_Clotting Mechanism.png

Blood does not normally clot in the blood vessels because there is not sufficient free thromboplastin to convert the inactive prothrombin into the active thrombin.


Related Discussions:- Clotting mechanism

Genetic recombination, Mutations are the only kind of variability generatin...

Mutations are the only kind of variability generating mechanism in prokaryotes and asexually reproducing organisms. But in eukaryotes where sexual recombination occurs, even in one

How hermaphrodite species present cross-fecundation, Is it possible for a h...

Is it possible for a hermaphrodite species to present cross-fecundation? There are hermaphrodite species of animals and plants that present cross-fecundation mainly because of

Criteria for identifying biodiversity hot spots, A simple method used to id...

A simple method used to identify areas of high conservation priority is the selection of countries according to highest species richness. Among the top 12 countries identified this

Lipids, Lipids All animal tissues contain lipids or fats as essential...

Lipids All animal tissues contain lipids or fats as essential components of cell membrane. It is also stored in certain tissues. Lipids are body's chief source of energy and

Create a punnett square, Q. Assume the gene for dimples, d, is recessive. T...

Q. Assume the gene for dimples, d, is recessive. Then assume that two individuals with the genotypes Dd and dd mate. Create a Punnett square for this mating and state the probabili

Mechanisms of neural plate formation, Mechanisms of Neural Plate Formation ...

Mechanisms of Neural Plate Formation You are familiar with the concept that the neurulation comprises of two processes i) The neural plate formation and ii) The neural t

Explain the completed test - most probable number test, Explain the Complet...

Explain the Completed Test - Most Probable Number Test? Coliform colonies on EMB or Endo agar are further examined by completed test by inoculating lactose broth and nutrient a

What do you mean by uricotelic and ureotelic excretions, Q Comparing toxici...

Q Comparing toxicity and the need for dilution in water how different are the uricotelic and ureotelic excretions? What are some examples of animals that present these respective t

Workgroup, Workgroup A Workgroup is a group of people who are working ...

Workgroup A Workgroup is a group of people who are working together on the same project. The members of such a group are usually (not always) located in close physical proximi

Pollution, Phosphate detergent as cause of water pollution

Phosphate detergent as cause of water pollution

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd