Chain lengthening of aldoses or killiani-fischer synthesis, Chemistry

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Chain Lengthening of Aldoses (Killiani-Fischer synthesis)

The conversion of an aldose to the next higher member includes the subsequent steps :

(a) Creation of a cyanohydrin.

(b) Hydrolysis of - CN to - COOH making aldonic acid.

(c) Conversion of aldonic acid into lactone through heating.

(d) The lactone is lastly reduced along with sodium amalgam or sodium borohydride to provide the higher aldose.

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