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Catecholamines increase activation of Ca2+ via beta-adrenergic receptors and the adenyl cyclase system.
Dopamine has both alpha and beta and dopaminergic effects. Its beta effects in the heart occur largely through the release of endogenous norepinephrine, which may be largely depleted in a failing heart. As such, the benefits of dopamine administration, if any, occur at low doses (e.g., 0.02 mg/kg per minute), where it may induce renal arterial vasodilatation. In general, it is employed in association with more potent inotropic agents (e.g., dobutamine).
Dobutamine characterized by an increase in cardiac output and a decrease in ventricular filling pressure with little change in heart rate. There is modest rise in arterial pressure and decrease in peripheral vascular resistance. The positive inotropic activity of dobutamine is mediated by direct stimulation of beta-adrenergic receptors in the myocardium.
Dobutamine infusion generally is begun at 2 µg/kg per minute and titrated to optimize cardiac output while reducing LV filling pressure. The major side effects of dobutamine are an excessive increase in heart rate with high doses and ventricular arrhythmias.
The article entitled "Life on Earth" is trying to make the point that RNA likely included before DNA. Forthis article which of the following is false? A. Chains of RNA nucleoti
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Transport with the Help of Membrane Protein Even though, the lipid bilayers do not permit the entry of polar molecules such as ions, sugars, amino acids, nucleotides and cell
Q. What are the events that mark the end and the beginning of the first interphase period? What happens inside the cell in this period? The initial interphase period is the G1.
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Metalimnion - Summer Stratification This zone lies below the epilimnion and above the hypolimnion and thus forms the intermediate layer which is non-circulating. The metalimni
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Q. How does biological diversity relate to the characteristics of the abiotic factors of an ecosystem? The ease of use of abiotic factors like light, mineral salts, moisture, h
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