Blood groups, Biology

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BLOOD GROUPS-

In R.B.C. on plasmalemma antigen or agglutinogen present form antibodies or agglutinines.

Blood groups are based on antigens.

1.      ABO SYSTEM -

  • Discovered by Leindsteiner. O group was discovered by De cestello and sturli.

S.no.

Blood Group

Antigen

Antibody

To take

To give

Genotype

1

A

A

B

A, O

A, AB

IA IA / IA i

2

B

B

A

B, O

B, AB

IB IB / IB i

3

AB

AB

-

A, B, AB, O

AB

IA IB

4

O

-

AB

O

A, B, AB, O

ii

2.      RH SYSTEM -

  • Discovered by Leindsteiner & Winner. Race and Taylor worked in it. Rh factor comes from Rhehsus monkey.
  • If Rh factor present Rh positive 97% in India and 80% in world.
  • If Rh factor absent Rh negative 3% in India and 20% in world.
  • If Rh positive blood is given to Rh negative person, first time no agglutination second time death occur.
  • If Rh negative mother is having Rh positive embryo, disease is erythroblastois foetalis (explained by Lavina, Leindsteiner & Winner).

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