Aortic stenosis, Biology

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Aortic Stenosis 

Aortic stenosis is due to an obstructive lesion that interferes with the blood flow out of the left ventricle. Depending upon the site of obstruction to the outflow of blood, the aortic stenosis may be divided into two categories. 

Pathophysiology 

Due to resistance to blood outflow from the left ventricle to the aorta, left ventricular hypertrophy occurs. There  is back flow of blood to the left atrium, causing increased pressure  in  left atrium which in  turn results  in  the increased pressure  in the pulmonary veins and pulmonary vascular congestion.  In case of severe obstruction the pulse pressure in  the aorta is narrowed.  


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