Why was it worthwhile to measure serum and red blood cell

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Questions:

1. What were the advantages to the approach selected by Chilean authorities of supplementing wheat flour with folate?

2. According to the surveillance program used in Chile, prevalence of neural tube defects was approximately 17/10,000 births before the fortification program was implemented, and 10/10,000 births afterward. What assumptions must you make in order to interpret the observed decline as resulting from folate fortification of wheat flour?

3. Why was it worthwhile to measure serum and red blood cell levels of folate before and after fortification, in addition to prevalence of neural tube defects in these periods?

4. Results of the surveillance program in Chile were also used - by proxy - as the basis of folate supplementation programs subsequently introduced in other Latin American countries. Comment on this as an approach to establishing public health priorities in low resource settings.

 

Reference no: EM133457386

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