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1. How are microsatellite markers scored (what are the alleles)?2. Why are microsatellites codominant markers?3. What are the advantages and disadvantages of using RFLP, AFLP, and microsatellite markers? If you don’t know any sequence information for the organism, which marker do you want to use?4. How does the modern Sanger sequencing technique work? What is the purpose of the ddNTPs? How is the order of nucleotides determined?5. What does a sequencing reaction contain?6. How does a cloning vector allow us to sequence an unknown segment of DNA?7. What are the advantages/disadvantages to Roche 454 Pyrosequencing and Solexa Illumina sequencing over the Sanger method?8. Which method was used to generate the first human genome? How much did it cost?9. How much did it cost to sequence the whole human genome using the HeliScope Sequencing System?
In a cohort study that found an association between alcohol consumption and bladder cancer, 20,000 middle-aged men were asked about their drinking habits and then tracked for 5-years to watch for development of cancer.
For example do you now understand the concept behind DNA fingerprinting. Did you find it difficult to determine the father in the paternity suit or the rapist.
A lilly from a true-breeding line with white flowers and short corollas (line A) is crossed to a lilly from a true-breeding line with black flowers and long corollas (line B).
Certain patients have a genetic disorder affecting a protein that provides support to the mitochondria of all the cells in the body. Yet the patients die of heart attacks.
age gender resting heart rate height weight body fat 14 male 70 bpm 510 120 pounds 10chris is a high school student
Compare and contrast gas exchange in lungs,gills and trachea. Give an example of a taxon that uses each. Describe the main components of each respiratory system
How can this result be explained and based on your explanation in part (a), what is the predicted result of a cross between a blue and a colorless strain?
Compare and contrast injuries in the central nervous system.
Dana has one dominant allele for brown eyes and one recessive allelle for blue eyes. What is dana's genotype and what is her phenotype?
In malignant hyperthermia, a person develops a life threatening high fever after taking certain types of anesthetic drugs. DNA sequencing of individuals with the disorder showed that in position 33 A nucleotide is substituted by G, in 513 - C by T..
Discuss how many ways can these chromosomes be assorted into gametes and how many different chromosome combinations are possible when crossing two unrelated flies?
What can be said about a human whose cells contain Barr Bodies.
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