Which mice would you use to only target dopamine cells

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Part A: You want to study the circuit that dopamine neurons of the substantia nigra (SN) makes with GABA cell in the dorsal striatum. You hypothesize that this pathway is important for maintaining fluid motor coordination. You decide to use optogenetic to silence the dopamine cells. Which viral construct would you use and with what light? Which mice would you use to only target dopamine cells? What would you expect to see if your hypothesis is correct.

 

 

Reference no: EM133450234

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