Which gene is associated with pathogenesis of this lesion

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A 66-year-old man presents for an annual evaluation. He has noticed several brown and black spots on his skin, but they have been stable for several years. The patient recalls that his father had similar skin lesions later in life. His medical history includes hypertension and hyperlipidemia, which are well-controlled with medication. Examination demonstrates numerous brown-to-black lesions that appear stuck on his back's skin surface. Histology shows hyperkeratosis with epidermis pseudo horn and horn cyst formation. Which gene is associated with the pathogenesis of this lesion?

 

 

Reference no: EM133605294

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