Reference no: EM133857347

Assignment:

Directions;

-read the case study and answer the questions

-ensure the answers are we'll explained

-arrange your work neatly

Case study; Let us look at some numbers. The rate of U.S. rubella infection in the year that a vaccine was released (1969) was 27 people per 100,000 as reported by the CDC. Within 10 years of distributing and administering the rubella vaccine, the rate had dropped to 2 people per 100,000. The current incidence of rubella in the U.S. is less that 0.1 people per 100,000. The CDC further reports that Polio was contracted at a rate of 10 people per 100,000 in 1955 in the U.S., the year Polio vaccinations began to be distributed. By 1975, the Polio infection rate had dropped to just 0.01 people per 100,000. The measles infection rate went from 400 thousand total cases in the year the vaccine came out (1963) to 20 thousand total cases five years later, and is now at less than 1 thousand cases per year.

Reflective quetsions

1. Explain the concept of TRP1 and origin as determined by the yeast DNA fragment

2. Concptualize on Tryptophan biosynthesis and chromosomal origin

3. Locate the YRP7 adjacent to the TRP1

4. Make the R stand out for the Replicative

5. Justify; A Yeast integrative plasmid cannot replicate as a plasmid inside the host?

6. What are the contributions of the Nucleotide catalysis in the concept of the URA3 gene?

7. How does the Yip5 carry URA3? What are the implications of this?

8. What is your understanding of Integrative when talking about Yips?

9. Locate the entire plasmid in the homologous recombination?

10. What is the role of homologous recombination in vector infection? Explain in details?