What is the mechanism of action of omeprazole

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Assignment:

A 48-year-old man presents for evaluation of heartburn. He reports a burning feeling in his chest after eating. It is worse when he eats spicy foods or tomato sauce. He is sometimes awakened at night with these symptoms. He has tried over-the-counter antacids and histamine H2 blockers with partial relief. He is on no medications regularly. His examination today is normal. An upper gastrointestinal (GI) x-ray series reveals gastroesophageal reflux. Along with appropriate diet and lifestyle modification recommendations, you prescribe omeprazole.

  1. What is the mechanism of action of omeprazole?
  2. Explain the pathophysiology of GERD.
  3. What is the mechanism of action of antacid medications?
  4. What are the mechanisms of action of H2 receptor blockers?
  5. What adverse effects should he be warned?

Reference no: EM133867544

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