What are the main objectives of xenobiotic metabolism

Assignment Help Chemical Engineering
Reference no: EM132190

QUESTION 1

(a) Handling operations for solid/powder substances are often a source of dust generation and are a source of exposure to hazardous substances in industries. Describe in details the measures that can be taken to prevent exposure during the following situations

  • Selection of materials
  • Bulk powder delivery and transfer
  • Dust generation at powder handling processes

(b) Discuss the four main mechanisms by which deposition of particles in the respiratory system may occur

(c) Discuss briefly on the two particle size fractions of interest in the workplace

QUESTION 2

(a) What are the four main stages of toxicokinetics?

(b) What are the main objectives of xenobiotic metabolism?

(c) Discuss in details the principles of biotransformation differentiating clearly the phases involved. Illustrate your answer with a relevant example

(d) Briefly discuss the four routes of excretion of hazardous substances from the body

QUESTION 3

(a) Discuss in details on four possible routes of entry of hazardous substances inside the body

(b) Graphically illustrate the Dose-Response Relation. Briefly discuss the following points on the dose-response curve

  • The No-effect level
  • The Threshold-dose
  • Lethal Dose 50% and Lethal Concentration 50%
  • Toxic Dose 50% and Toxic Concentration 50%

QUESTION 4
(a) Describe the following combined effects that may occur in the workplace on exposure to hazardous substances. Support your answer with relevant example of such substances

The combine effects are as follows-

  • Additive effects
  • Synergistic effects
  • Potentiation
  • Antagonism
  • Independent

(b) Discuss on three allergic conditions that can occur on exposure to chemical substances that can lead to respiratory sensitization. Support your answer with an example of such substances

(c) Briefly describe on the causes and symptoms of acute irritation of the upper and lower respiratory tract

Reference no: EM132190

Reviews

Write a Review

 

Chemical Engineering Questions & Answers

  Adsorption and membranes processes

Application of reverse osmosis principles for the desalination of sea water

  Evaluation of a new chemical manufacturing process

Prepare the design and evaluation of a new chemical manufacturing process.

  Baffled tank with a six blade turbine agitator

Equal rates of mass transfer for the production of the fine chemical are required. This is often required for certain types of organic synthesis.

  What are the four main stages of toxicokinetics

The effect of a hazardous substance depends on the concentration of the substance that is present in the body's systems. The concentration depends on the stages of toxicokinetics What are the four main stages of toxicokinetics

  The bridging principles for classification of mixtures

Describe the main purpose of the Globally Harmonised System of Classification and Labelling of Chemicals - Outline the bridging principles for classification of mixtures

  Materials chemistry find potential energy between two atoms

The potential energy between two atoms A and B are constants and r the interatomic separation distance.

  Adsorption and membrane processes

Adsorption and Membrane Processes

  Solve the initial value problem

Use Laplace transformation to solve the initial value problem

  Calculate the molar fraction of system in the vapor phase

Calculate the molar fraction of the system in the vapor phase

  Why a substance heated at a fast rate

Why a substance is being heated at a fast rate the temperature of decomposition

  Implications of the future of fabrication for international

Implications of the future of fabrication for international trade, transportation, and logistics

  Design variables necessary for sizing equipment

Assist with the setting of design variables necessary for sizing equipment

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd