Unintentional weight loss

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A 37-year-old previously healthy woman presents to your clinic for unintentional weight loss. Over the past 3 months, she has lost approximately 15 lbs. without changing her diet or activity level. Otherwise, she feels great. She has an excellent appetite, no gastrointestinal complaints except for occasional loose stools, a good level of energy, and no complaints of fatigue. She denies heat or cold intolerance. On examination, her heart rate is 108 beats per minute, her blood pressure is 142/82 mmHg, and she is afebrile. When she looks at you, she seems to stare, and her eyes are somewhat protuberant. You note a large, smooth, nontender thyroid gland, a 2/6 systolic ejection murmur on cardiac exam, and that her skin is warm and dry. There is no tremor.

Questions

1. What is the most likely diagnosis?

2. How would you confirm it?

Reference no: EM133632794

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