Substantial impact on morbidity and mortality

Assignment Help Science

Reference no: EM133858756

Question

Opioid use disorder (OUD) is a significant public health challenge worldwide with a substantial impact on morbidity and mortality. Out of 600,000 deaths attributed to drug-related in 2019, 80% of these deaths are related to opioid use disorder and 25% of those deaths related to opioid overdose reported by World Health Organization (WHO, 2023). An effective treatment is crucial for managing and overcoming addiction. Naloxone is an opioid antagonist, included in Suboxone primarily to deter potential misuse by blocking the effects of other other opioids if they are taken concurrently (Blazes and Morrow, 2020). Suboxone is a combination medication of buprenorphine and naloxone and is widely used in the treatment of OUD. Blazes and Morrow (2020), reports that when these products are taken as sublingual tablets, naloxone has minimal bioavailability and does not interfere with buprenorphine's efficacy. But when someone misuse it by injecting it, naloxone becomes active precipitating withdrawal symptoms by blocking mu-opioid receptors. This encourages patients to adhere to the intended route of administration. This reduces the risk of misuse and diversion.

Reference no: EM133858756

Questions Cloud

What additional thoughts feelings or questions are you left : What additional thoughts, feelings, or questions are you left with after learning more about American Indian boarding schools?

New murmur during near syncopal episode workup : Your 51-year-old female patient has been diagnosed with a "new murmur" during a near syncopal episode workup.

Mental health services and substance abuse treatment : Tuesca and family when it comes to mental health services and substance abuse treatment.

Describe how dnp leader accesses primary data sources : Describe how the DNP leader accesses primary data sources from credible resources. As you review the literature, look for articles

Substantial impact on morbidity and mortality : Opioid use disorder (OUD) is a significant public health challenge worldwide with a substantial impact on morbidity and mortality.

Which vaccines are live and what is live vaccine : You are caring for a 6-month-old infant in Pediatric Clinic who is present for Well Child Check-up with both parents.Which vaccines are live? What is a live

Identify the importance of medication reconciliation : Apply the concept of safety as it relates to medication administration. Identify the importance of medication reconciliation.

Create step-by-step instructional pamphlet : Create a step-by-step instructional pamphlet for other nurse practitioner students.The primary purpose of the pamphlet is to list the strategies

Risk and side-effect consideration : Select a vulnerable patient from the list provided. Consider age, birth-assigned sex, FDA approvals, and risk and side-effect consideration.

User Account

All Pages