Sparing diuretics due to increased risk of hyperkalemia

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Use caution when combining ACEIs with potassium-sparing diuretics due to an increased risk of hyperkalemia. ACEIs and ARBS will precipitate acute renal failure when bilateral renal artery stenosis is present. Alpha-blockers are not first-line drugs for HTN unless the patient has pre-existing benign prostatic hypertrophy (BPH). Women who have both HTN and osteopenia/osteoporosis should take thiazides to help slow calcium loss, stimulate osteoclasts, and reduce bone loss. Cardio-selective blocking agents should be utilized when treating heart failure. Myalgia or muscle pain is common with statins. If muscle pain is accompanied by dark urine, rhabdomyolysis should be ruled out. Patients on simvastatin and lovastatin should avoid grapefruit juice and should not take macrolides.

Reference no: EM133690339

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