Probability of a failing to detect

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A medical team wants to evaluate the effectiveness of a new drug that has been proposed for people with high intraocular pressure (IOP). Prior to running a full-scale clinical trial of the drug, a pilot test was run using 10 patients with high IOP values. The n =10 patients had a mean decrease in IOP of = 15.2 mm Hg with a standard deviation of the 10 IOPs equal to s = 9.8 mm Hg after 15 weeks of using the drug. Determine the appropriate sample size for an a α = .01 test to have at most a .10 probability of a failing to detect at least a 4 mm Hg decrease in the mean IOP.

Reference no: EM131019859

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