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Understanding the underlying pathophysiology of peripheral vascular disease is crucial for advanced practice nurses to effectively diagnose, manage, and educate patients on this condition. In this week's discussion, we will explore the pathophysiology of peripheral vascular disease (PVD). Please address the following in your post: Describe the key pathophysiological mechanisms involved in the development of PVD. Consider the roles of atherosclerosis, endothelial dysfunction, and inflammation. Identify the common risk factors that contribute to PVD. Discuss how modifiable (e.g., smoking, diabetes) and non-modifiable (e.g., age, genetics) risk factors influence disease progression. Explain how PVD leads to the clinical manifestations seen in patients. Include symptoms such as intermittent claudication, rest pain, and critical limb ischemia. Discuss the impact of PVD on systemic circulation and its potential complications. How does PVD relate to cardiovascular disease and increased risk for events such as myocardial infarction or stroke?
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