Neurological and musculoskeletal pathophysiologic processes

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A 58-year-old obese white male presents to ED with a chief complaint of fever, chills, pain, and swelling in the right great toe. He states the symptoms came on very suddenly and he cannot put any weight on his foot. Physical exam reveals exquisite pain on any attempt to assess the right first metatarsophalangeal (MTP) joint. Past medical history was positive for hypertension and Type II diabetes mellitus. Current medications include hydrochlorothiazide 50 mg po q am, and metformin 500 mg po bid. CBC normal except for elevated sedimentation rate (ESR) of 33 mm/hr and C-reactive protein (CRP) 24 mg/L. Metabolic panel normal. Uric acid level 6.7 mg/dl.

1. Identify and explain thoroughly the neurological and musculoskeletal pathophysiologic processes that would account for the patient presenting these symptoms. (gouty arthritis)

2. Any racial/ethnic variables that may impact physiological functioning.

3. How these processes interact to affect the patient.

Reference no: EM133881682

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