Malignancy progressed rapidly despite treatment

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The malignancy progressed rapidly despite treatment, resulting in the following distressing symptoms:??????? the loss of his tongue made speech completely unintelligible, there was also ???????extensive loss of teeth making it very difficult to swallow, ???????severe facial disfigurement, ???????the necrotic non-healing oral ulcer caused severe mal-odour, as well as significant ???????facial pain.

At first, Mr Murphy's symptoms were relatively well controlled with:

Methadone (50 mg thrice daily),

immediate-release morphine sulfate (20 mg every four hours,) for breakthrough pain and, on an "as needed" basis,

haloperidol (0.5 mg every six hours) for nausea and vomiting,

lorazepam (0.5 mg every four hours) for anxiety,

Discuss why this combination of medication has been prescribed?

Reference no: EM133951451

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