Large class of drugs some were discovered in nature

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Classes of Antifungal Drugs In this large class of drugs some were discovered in nature, but most are synthetically made. Griseofulvin (ringworm) is a metabolic product of a Penicillium mold; nystatin and amphotericin B (systemic infections) come from Streptomyces bacteria; and the newest members, the echinocandins (systemic infections), are found in Aspergillus molds. The echinocandins include three drugs: anidulafungin, caspofungin, and micafungin. Undecylenic acid (athlete's foot) is an organic fatty acid derived from natural castor oil from the castor bean plant. The rest of this class is man-made. To make it a little easier to remember, the largest and most frequently used synthetic drugs are the imidazoles and triazoles. This group includes any drug name ending in azole: econazole, itraconazole, ketoconazole, and voriconazole. There are 11 azole drugs listed in Table 42.2 with clinical value as antifungal agents. Antifungal drugs are selective in their spectrum of activity and site of action. As a rule, these drugs have no antibacterial or antiviral activity and affect only certain pathogenic fungi. What are the drug class and drug name?

Reference no: EM133875440

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