Key mechanisms that contribute to migraine development

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Reference no: EM133876767

Question

Pathophysiology Overview: Based on your exploration, summarize the key mechanisms that contribute to migraine development. How do cortical spreading depolarization, the trigeminovascular system, and inflammation interact in the migraine process? Genetic and Environmental Influences: Discuss how genetic predispositions and environmental triggers, such as stress and hormonal changes, may influence the pathophysiology of migraines. What is the role of epigenetics in migraines? Treatment Implications: How does the understanding of neurotransmitter involvement (e.g., serotonin, CGRP) and vascular changes inform current pharmacological treatments for migraines? Which treatments target these specific pathways, and what are their mechanisms of action? Reflection: In a brief paragraph, reflect on how an understanding of migraine pathophysiology can influence your approach to diagnosing and managing patients with migraines in clinical practice.

Reference no: EM133876767

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