Enhance insulin sensitivity in peripheral tissues

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Rephrase: Metformin: Metformin is widely considered as the initial treatment for type II diabetes due to its ability to enhance insulin sensitivity in peripheral tissues, lower hepatic glucose production, and decrease intestinal glucose absorption. A typical starting dose of 1000 mg twice daily is usually prescribed and may be adjusted based on the patient's glycemic response and ability to tolerate the medication. (Corcoran & Jacobs, 2023). Glipizide: Glipizide is a medication that stimulates insulin release from pancreatic beta cells, belonging to sulfonylurea class. Increasing the dose to 20 mg twice daily aims to enhance insulin secretion to help lower Jose's elevated blood glucose levels. Diltiazem: For the treatment of high blood pressure and chest pain, it is recommended to continue with the current dosage of Diltiazem, which is a calcium channel blocker. Addition of Insulin It may be necessary for Jose to undergo insulin therapy due to his significantly elevated fasting blood glucose and high HgA1C level. Typically, basal insulin is initiated to provide background insulin coverage throughout the day, and the dose is adjusted based on blood glucose levels and response.

Reference no: EM133762650

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