Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Part A. True or FalseAs indicated on your Parscore sheets, fill in A for True or B for False.
1. The efficacy of an agonist is determined in large part by the number of available or "active" receptors with which to bind. TRUE!
2. The Ras-Raf-MAP kinase pathway is activated upon stimulation of receptor tyrosine phosphatases. FALSE! (kinase, Trk-Rs)
3. Intracellular signaling through Gq-coupled receptors does not involve direct activation of second messenger systems. TRUE! ... (PLC-BETA → PI(4,5)P2 → DAG/IP3 → then Ca2+.... PKC)
Multiple Choice Answers (1 mark each):You are to select the BEST of the lettered alternatives provided for each question. Fill in the appropriate selection on your Parscore sheet. Choose only ONE answer for each question. Each question is worth 1 mark each. 4. Of the following, which is TRUE regarding receptors? a) A receptor has an endogenous ligand that interacts with a specific site on the receptor.b) The capacity of a ligand to bind to a receptor is determined by the charge, shape and size of both the ligand and the receptor.c) The intensity of the effect of the binding of a ligand to a receptor depends upon the percent of total receptor occupied by the ligand.d) All of the above. 5. Activation of which of the following kinases is dependent upon intracellular cAMP levels? a) protein kinase A (PKA) b) protein kinase C (PKC) c) mitogen-activated protein kinase (MAPK) d) calcium-calmodulin kinase II (CAMK II) Open-ended Questions. Good answers should be concise and logically organized. Answers should be written on each page under the appropriate question and can continue to the back if necessary. Answers can be in point form or can be illustrated but the information MUST be complete in order to receive full marks. Use the number of points awarded for each question as a guide for the number of steps involved. You have a full page to answer each question below but should you need more space, please use the back of the page but INDICATE so (or else a portion of your answer may be missed). 6. Explain in detail at least 2 ways in which stimulation of a receptor tyrosine kinase could lead to an increase in CREB-mediated transcription of a gene . (16 marks)
Will the present value of your winnings using an interest rate of 13% be onehalf the present value of your winnings using an interest rate of 6.5%? Why or why not?
Gemstone Corporation has a sales budget for next month of $600,000. Cost of goods sold is expected to be 30 percent of sales. All goods are purchased in the month used and paid for in the month following purchase.
1 during january its first month of operations knox company accumulated the following manufacturing costs raw materials
Fixed assets are purchased and retired frequently. Given this frequent change, why are clear accounting records of fixed assets necessary?
Which of the following is the correct entry to record the payment by Underwood Inc., within the 10 days if the company uses the periodic inventory system and the gross method to record purchases?
Prepare an appropriations ledger, using columns for Encumbrances (Dr. and Cr.) Expenditures and Available Balance.
A firm pays a $4.90 dividend at the end of year one (D1), has astock price of $70, and a constant growth rate (g) of 6 percent. Compute the required rate of return.
Identify from the list below the type of disposition of a passive activity where the taxpayer keeps the suspended losses of the disposed activity and utilizes them on a subsequent taxable disposition.
Madison Company issues $5,000,000 face value, 12%, 5-year bonds payable on December 31, 2005. Interest is paid semiannually each June 30 and December 31. The bonds sell at a price of 97; Madison uses the straight-linemethod of amortizing bond disc..
the mason manufacturing company began construction of a building to be used as its office headquarters. the building
barnett industries inc. issued 600000 of 8 bonds on january 1 2013. the bonds pay interest semiannually on july 1 and
fullerton waste management purchased land and a warehouse for 640000. in addition to the purchase price fullerton made
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd