Discuss cellular patho physiological processes

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Questions

1. Discuss the cellular patho physiological processes involved in Sickle Cell Anemia in an Adolescent Patient. How do these relate to his symptoms?

2. Identify the genetic mutation responsible for Sickle Cell Anemia in an Adolescent Patient and its mode of inheritance.

3. Explain how sickle cell disease affects the immune system.

4. Describe how current treatments, such as hydroxyurea, target the cellular alterations of the disease.

5. What patient-specific or culturally sensitive education might an APRN provide to help Marcus adhere to his treatment plan?

Patient: Marcus, a 16-year-old African American male Chief Complaint: Severe joint and chest pain, fatigue, shortness of breath History of Present Illness: Marcus presented to the emergency department with complaints of severe pain in his knees, lower back, and chest. His mother reports that Marcus has been increasingly tired, has missed school due to fatigue, and is experiencing shortness of breath after climbing stairs. She also notes a low-grade fever and yellowing in the whites of his eyes.

Past Medical History:

• Diagnosed with sickle cell disease at birth

• Frequent hospitalizations for pain crises

• On hydroxyurea therapy, though with inconsistent adherence

• Up to date on vaccinations Family History: Mother is a carrier

Reference no: EM133900746

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