Reference no: EM133754004
Case study : Peptic ulcer
A 68-year-old Alice Benson was referred to a Gastro-enterology Clinic from primary care provider due to consistent discomfort and significant weight loss. She had a tarry stool which she had never experienced before. She presented with a 2-month history of burning pain in the epigastric region of abdomen and chest which radiated toward her back. Alicia's pain worsened after taking aspirin and drinking coffee, and was relieved after taking antacids, Ranitidine. She had previously lost 5kg in 2 months due to decreased intake caused by the feeling of bloating, early fullness and stomachaches. She also reported nausea/vomiting and dark color stools. She expressed concern especially because the food appeared undigested when she vomited. She also reported doubling her NSAID intake due to increased knee pain. She looked pale and exhausted when she entered the clinic.
Vital Signs and Measurements
1. BP: 135/85 mm Hg
2. HR: 99 bpm
3. RR: 23/min
4. Temperature: 36.1 °C
5. Pulse oxygenation: 94%
Past medical history
- Gastritis with Helicobacter pylori (H. pylori) infection, diagnosed 5 years ago.
Resolved with triple therapy consisted of pantoprazole plus 2 antibiotics.
- Heart attack 3 months ago, has started taking aspirin since then.
- Osteoarthritis, diagnosed 3 years ago. Long-term use ibuprofen (NSAIDS) since diagnosis.
- Chronic obstructive pulmonary disease, diagnosed 11 years ago.
- Diabetes Mellitus and hypertension diagnosed 6 years ago.
- No surgical history.
Pertinent social history
- Hobbies include drinking, eating spicy food, watching dramas and talk show.
- Has smoked for 30 years, even after the diagnosis of COPD, still cannot quit smoking.
QUESTIONS:
1. What is a likely medical diagnosis for A.B?
2. What are the common sites of peptic ulceration in the gastrointestinal tract and why do peptic ulcers form in these locations?
3. List the risk factors for Alicia in the formation of peptic ulcer/s.
4. How is H. pylori diagnosed as the causative agent for peptic ulcer disease?
5. Differentiate between gastric and duodenal ulcers.
6. What are the common signs and symptoms of a peptic ulcer?
7. What are the possible complications of peptic ulcers?
8. How do NSAIDs contribute to peptic ulcer formation?