Reference no: EM133946324

Question: Genetics in Practice - make sure you know the answers to the questions I asked in the chapter PowerPoint.
Differentiate between genomics and proteomics.
Describe the differences between the Human Genome Project (HGP) and the Human Proteome Project (HPP) in both their purpose and who they are examining humans (HGP focused on humans as whole organisms, while HPP is looking at different cell types within humans)
Define structural genomics and functional genomics in relation to these two terms.
Describe the approach to sequencing a complex genome that ended up working for the HGP, including the role of genetic linkage mapping, physical mapping, map-based sequencing and whole genome shotgun sequencing.
**You will NOT be tested on NextGen or newer sequencing methods (no questions on this).
Describe what a Single Nucleotide Polymorphism (SNP) is and why a single SNP does not provide much information about a person or group of people, but a haplotype can. Get online assignment help – 100% Original & AI-Free Content.
Explain how a Genome-Wide Association Study (GWAS) uses genome sequence and SNP information to being to analyze possible causes of a genetic condition, including the limitations of these studies.
Identify the interdisciplinary fields involved in bioinformatics and why.
Describe what metagenomics is and that it primarily focuses on microbial communities (and why helpful there)
**You will NOT be tested on using BLAST to analyze homologues or orthologs or RNA-seq (no questions on this).
Describe what a microarray is and how it is used by scientists to analyze gene expression differences between cell types or groups of individuals to identify genes involved in a process (such as cancer patients or developmental changes)
For comparative genomics, review and be able to discuss basic features of prokaryotic versus eukaryotic genomes (general size of genome, # of genes and gene "density") and the impact of transposons in repetitive DNA in eukaryotic genomes.