Describe the two signal hypothesis

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Questions

1. What is the product and its colour when alkaline phosphatase reacts with its most used substrate in an ELISA?

2. Of the following individuals with ELISA detectable measles antibodies determined by ELISA, which individual is likely to have the highest level of antibody-based protection from disease?

ELISA end-point titre values: Individual 1 = 1:32; Individual 2 = 1:16; Individual 3 = 1:512; Individual 4 = 1:64; Individual 5 = 1:1,024; Individual 6 = 1:2

3. Give two examples of Toll like receptors. What does each recognise?

4. List each of the molecules that form an immunological synapse. To what does each bind?

5. Describe the two signal hypothesis. Why is is required?

6. How can a therapeutic vaccine improve T cell immunity against cancer?

7. What are the three "professional" antigen presenting cell types?

8. Explain the Th1/Th2 dichotomy and the rationale for it.

Reference no: EM133932609

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