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A.C. is a 54-year-old African American woman who is 5'8" tall, weighs 130 lb., and presents complaining of amenorrhea for the past 7 months. She wakes up at least six times a night with hot flashes and experiences them at least 10 times a day. She is extremely uncomfortable and sleep deprived. At the visit, a pap smear is completed and the mammogram is normal. Her follicle-stimulating hormone level is 32 international units/mL. She has no family history of breast cancer, but her mother has osteoporosis and glaucoma. What drug therapy would be prescribed? (Support your response with the appropriate evidence-based recommendations.) Describe the kinetics and dynamics for the prescribed drug. Discuss specific patient education based on the prescribed therapy. List two adverse reactions for the selected agent that would cause a change in therapy. What nonpharmacological treatments would you recommend to A.C.? Why?
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