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Preterm birth is dened as the condition of not reaching a certain gestational period. In healthy women with low-risk pregnancy, there may also be a certain proportion of premature infants. According to the data of the World Health Organization, preterm infants (PIs) refer to those born before 37 weeks of pregnancy or infants less than 259 days from the rst day of a woman's last menstruation [1]. Since China has carried forward an overall two-child policy, the number of women with advanced maternal age has gradually increased, resulting in an increasing in the rate of premature delivery [2]. Unlike normal babies, PIs are with shorter gestational age, lighter weight, and undeveloped or immature organs; thus, they are prone to suer from complicated diseases, which threaten the development of newborns [3]. According to statistics, the global PIs mortality rate has reached 20.8% and is on the rise, posing an important global health issue [4]. anks to the continuous development of medical technology, the rescue rate and survival rate of PIs have been signicantly improved [5]. However, due to the lack of intrauterine nutrition reserve, PIs have many adverse characteristics and will still face long-term growth and development.
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