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Cancer epidemiology and risk factors

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Reference no: EM132635348

Neoplastic Alterations in Cells

Cancer Epidemiology and Risk Factors

1. Outline the common risk factors associated with the development of cancer

2. Along with lung cancer what other cancers are associated with tobacco use?

3. Describe the pathophysiology of sustained proliferative signaling relative to cancer

4. Describe the pathophysiology of evasion of cell growth suppressors and mechanisms that allow evasion of normal immune protection relative to cancer

5. Describe the pathophysiology of enabling replicative immortality relative to cancer

6. Describe the pathophysiology of tumor producing inflammation relative to cancer

7. Describe the pathophysiology of genomic instability relative to cancer

8. Describe the pathophysiology of resisting apoptosis relative to cancer

9. Describe the pathophysiology of deregulation of cellular energetics relative to cancer

Nomenclature and Grading/Staging of Tumors

1. Differentiate between the characteristics of benign and cancerous tumors and cancer in situ

2. Outline the grading/staging of tumors

Carcinogenesis and Metastasis

1. Discuss the processes of initiation, promotion and progression in the multistep process of cancer development

2. Discuss the process of tumor cell metastasis

Childhood Cancers

1. What germ layer do most childhood cancers arise?

2. Which chromosomal abnormalities are associated with childhood cancers?

3. Aside from leukemia, what are the locations/types of other childhood cancers?

Reference no: EM132635348

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