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1. Cystic fibrosis is a chronic lung and digestive disease caused by a mutation in the CFTR gene on chromosome 7. In the United States approximately 39 in 10,000 individuals are affected with the recessive condition cystic fibrosis, 323 in 10,000 individuals are unaffected carriers, and 9,638 out of 10,000 individuals are unaffected non-carriers. Although there are over 1,000 known mutations in the CFTR gene that can lead to cystic fibrosis, we can determine the overall frequency of recessive alleles in the U.S. population.a)Calculate the observed frequency of CFTR alleles :CFTR dominant (unaffected) alleles =CFTR recessive (cystic fibrosis) alleles =b)The expected frequency of CFTR genotypes :Homozygous dominant (unaffected) =Heterozygous (unaffected carriers) =Homozygous recessive (affected) =c)Next, use the following chi-squared analysis table to determine if the U.S. population is in Hardy-Weinberg equilibrium for the recessive condition, cystic fibrosis.Degrees of Freedom = 1Critical Value = 3.84
Determine which organ system are msot invovled with homeostasis and discuss the role of SNARE in exocytosis.
In this week's experiment, we will examine the technique of random sampling as a tool for the estimation of large populations.
Suppose that red reen color blindness is a recessive sex linked trait. A normal man mates with a color blind woman, what can we expect their children to be? Explain your answer.
What is the most likely defect associated with the Ser63 deletion mutant. How would you design an experiment to test your hypothesis using culture cells and the expression construct of wild-type and Ser63 deletion mutant of P0.
While two monohybrid round squashes are crossed, the offspring ratio is ¼ flat, ½ oblong, ¼ round. Squash shape is therefore controlled by incomplete dominance. What offspring ratio would you expect from a cross between a plant with oblong fruit and ..
create a specific experiment to measure the rate of cellular respiration in an organism of your choice
Comb shape in chickens represents a classic example of gene interaction. 2-gene pairs interact to influence shape of the comb. The genes for rose com and pea comb together produce walnut comb.
Albinism is a rare genetically inherited trait that is only in phenotype of homozygous recessive individuals. The most characteristic symptom is a marked deficiency in the skin and hair pigment melanin.
The internal structure of the cells of many protists is much more complex than cells of multicellular organisms. Does this mean that protists is engaged in more complex activities than muticellular organisms?
Give a probable explanation for the inheritance of the melanotic mutation. A 19 year old model for Glamour magazine tripped over an extension cord causing injury to her epidermis. She is afraid injury will leave a scar. Based on your information of r..
The endocrime and nervous system are main regulating systems of the body. However, the nervous system has been compared to an airmail delivery system, and endocrime system to the pony express. In brief explain this comparison.
The following recombination frequencies were found for four (A, B, C, and D) on the same chromosome; between genes A and B - 45 percent, between genes C and D- 10 percent,
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