Associated with increased risk for overdose and death

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Methadone is associated with increased risk for overdose and death. Which statement accurately explains the basis for this phenomenon? Methadone is associated with increased risk for overdose and death. Which statement accurately explains the basis for this phenomenon? It is an irreversible mu opioid agonist and its actions cannot be reversed Methadone is a synthetic opioid and therefore is more potent opioid than natural opioids. Neurotoxic metabolites of methadone accumulate in situations of renal impairment The half-life, duration of action, and time to steady state are long and variable requiring careful dose titration.

Reference no: EM133632541

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Associated with increased risk for overdose and death : Methadone is associated with increased risk for overdose and death. Which statement accurately explains the basis for this phenomenon?

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