Adenoma of corticotrope cells in anterior pituitary

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1. A 34-year-old female patient is referred to imaging. The MRI reveals that the patient has a benign adenoma of corticotrope cells in the anterior pituitary. The result is uncontrolled production of ACTH. Explain why this benign tumor will result in loss of homeostasis and how she will clinically present (symptoms and signs).

2. A 23-year-old male patient with asthma experiences an episode of severe asthmatic attacks due to seasonal allergies. His physician prescribes a high dose or oral PREDNISONE (synthetic cortisol) to manage his symptoms. The patient beings to feel better and stops taking the medication cold turkey rather than following the taper-down schedule prescribed. Based on your understanding of homeostasis, explain why this patient decompensates and ends up in the ER.

Reference no: EM133254253

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