Minimization, Advanced Statistics

Minimization is the method or technique for allocating patients to the treatments in clinical trials which is usually the acceptable alternative to random allocation. The procedure ensures the balance between the groups to be compared on prognostic variables, by allocating with the high probability next patient to enter the trial to whatever treatment would minimize the total imbalance between the groups on prognostic variables, at that stage of trial.

Posted Date: 7/30/2012 3:50:18 AM | Location : United States

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