Mechanism of carcinogenesis, Biology

Mechanism of Carcinogenesis

In the preceding sub-section you learnt that carcinogenesis is a multistep process. Even though cancer may be caused by many agents chemical, physical and viral they all have a common pathway that are, damage to DNA. This damage or alteration of the normal DNA of the cell can be affected mainly in two ways. Either the common genes are mutated or as in the case of viral agents, abnormal genes are inserted in the host cell which encodes abnormal proteins the question may arise that of the genes of the normal cell on mutation give rise to neoplastic cells? We said earlier that neoplastic cells arise while normal cells somehow escape the clutches of cell growth regulatory mechanisms. Hence, genes that are responsible for regulating cell growth and differentiation would be the observable targets of mutation. Research over the years has revealed that two major types of genes play a role in cancer induction. The first is a set of genes that regulate cell growth and differentiation. These genes are termed as proto-oncogenes and their mutated versions that can cause cancer are called oncogenes. The second is a set of tumor-suppressor genes as well called anti-oncogenes whose common function is to prevent overgrowth of cells.

Posted Date: 1/31/2013 7:48:58 AM | Location : United States







Related Discussions:- Mechanism of carcinogenesis, Assignment Help, Ask Question on Mechanism of carcinogenesis, Get Answer, Expert's Help, Mechanism of carcinogenesis Discussions

Write discussion on Mechanism of carcinogenesis
Your posts are moderated
Related Questions
What are the main structures of chloroplasts? Chloroplasts are included by two membrane layers, the outer and the inner membranes. Inside the organelle the formative unit is kn

You have 875 mL of a 0.37 M acetic acid solution. What volume (V) of 1.20 M NaOH solution must you add in order to prepare an acetate buffer of pH = 4.36? (The pKa of acetic acid i

uses of conductometry in biological experiments

The calorific value of a fuel can be theoretically determined by using dulong's formula. It is assumed that heat evolved comes from the combustion of carbon, hydrogen, and sulphur

DIGESTIVE SYSTEM IN COCKROACH ALIMEN T A R Y CANAL 6-8 cm. long. Coiled, present from mouth to anus. Differentiated into 3 parts -      1. Foregut            2. M

Equal Distribution of Hereditary Material: In mitosis the heredity material is equally distributed in the daughter cell. 2.No Change in Genetic Information: As there is no

What is the cost-benefit relationship regarding sewage treatment as a method to fight water pollution? To treat sewage is much cheaper for society. The non treated sewage pollu

What are the main cytoplasmic structures present in animal cells? Ans) The major cytoplasmic structures of the cell are the centrioles, the cytoskeleton, lysosomes, mitochondria

Which physical elements contributed to the great amount of available energy on the primitive earth at the time of the origin of life? 3.5 billion years since the water cycle wa

What is an oligopeptide? How is it different from a polypeptide? Peptide is the molecule produced by the union of amino acids through the peptide bond. Oligopeptide is a peptid