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Explain Some Functions of Riboflavin?
Protective role: Riboflavin protects the octodermal tissues and prevents lesions of the skin, eye and nervous system. Riboflavin ameliorates cardiac damage and also has antimalarial effects.
Regulatory functions: Riboflavin is concerned with the regulatory functions of some hormones involved in carbohydrate metabolism.
Other function: Riboflavin interrelates with other B vitamins, notably niacin, which requires FAD for its formation from tryptophan, and vitamin B6 which requires FMN for conversion of the phosphates of pyridoxine and pyridoxamine to the coenzyme pyridoxal 5'-phosphate (PLP). Riboflavin deficiency slows down the uptake of pyridoxine and decreases the conversion of pyridoxine to its metabolites.
It is immune difficult mediated hypersensitivity. Typical manifestations contain rheumatoid arthritis, serum sickness, necrotizing etc.
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