Explain rifabutin, Biology

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.


Posted Date: 6/26/2013 3:46:10 AM | Location : United States

Related Discussions:- Explain rifabutin, Assignment Help, Ask Question on Explain rifabutin, Get Answer, Expert's Help, Explain rifabutin Discussions

Write discussion on Explain rifabutin
Your posts are moderated
Related Questions
Explain Photolithoautotrophs - Nutritional Types of Microorganisms? These microorganisms use light as an energy source, inorganic substance as electron source and CO 2 as the

Q. What is the general equation of the aerobic respiration (also representing phosphate and ADP)? The general  chemical equation of the aerobic respiration is: C 6 H 12 O 6

What would happen to a cell and its offspring if the cells did not go by a G1 phase during their cell cycle? Describe Without a G1 growth phase, the cells would not grow to th

Mixed Tricuspid Stenosis and Regurgitation:  Rheumatic involvement of the tricuspid valve is often seen in association with involvement of mitral and rarely aortic valve. Isolated

In what way do investigations build scientific knowledge?

Explain the Digestion of carbohydrates? You are aware that 60-70% of energy is supplied by the dietary carbohydrates which are primarily present as polysaccharides (starch) fol

Define fluorides Metabolism? Soluble fluorides, even at high intake levels are almost completely absorbed from gastrointestinal tract. These include aqueous solutions of fluori

Total Arterial Re-vascnlarisation :  In total arterial re-vascularisalion (TAR) end of the right internal mammary artery (RIMA) or radial arlery (RA) is anastomosed to the side of

What are the classes in Phylum coelenterata?

Another important genus of mycotoxin producers is Fusarium, many species of which produce members of the trichothecene family of mold metabolites like deoxynivalenol, neosolaniol a