Bovine leukemia, Biology

Bovine leukemia


Bovine leukemia, also known as bovine lymphosarcoma or leucosis, is a lymphoproliferative neoplastic disease of bovines. The virus belongs to genus Deltaretrovirus in the family Retroviridae. Oncogenesis depends on the integration of bovine proviral v-onc gene into cellular DNA. Transmission of Bovine leukemia virus occurs primarily by the transfer of lymphocytes between animals. The virus can be transmitted to the fetus but usually less than 40% calves born to infected dams are infected at birth.


Clinical signs:
The symptoms of this disease are persistent lymphocytosis, leukemia and or lymphosarcoma in cattle. The lymphoid tumors are seen in lymph nodes, abomasums, heart, spleen, kidneys, uterus, spinal meninges, and brain.


Diagnosis: Antibodies to bovine leukemia virus antigens are demonstrated by immunodiffusion, radioimmunoassay, enzyme immunoassay, syncytium-inhibtion assay and complement-fixation test. The diagnosis is aided by the hematologic observations including lymphocytosis and the presence of immature lymphocytes. Electron microscopy, infectivity assay in cell-culture systems and sero-epidemiological observations provide a confirmatory diagnosis.


Prevention and control: Identification of the affected animals by serological testing followed by culling is the only available method of controlling this disease.Bovine leukemia, also known as bovine lymphosarcoma or leucosis, is a lymphoproliferative neoplastic disease of bovines. The virus belongs to genus Deltaretrovirus in the family Retroviridae. Oncogenesis depends on the integration of bovine proviral v-onc gene into cellular DNA. Transmission of Bovine leukemia virus occurs primarily by the transfer of lymphocytes between animals. The virus can be transmitted to the fetus but usually less than 40% calves born to infected dams are infected at birth.

 

Posted Date: 9/17/2012 9:15:02 AM | Location : United States







Related Discussions:- Bovine leukemia, Assignment Help, Ask Question on Bovine leukemia, Get Answer, Expert's Help, Bovine leukemia Discussions

Write discussion on Bovine leukemia
Your posts are moderated
Related Questions
DNA TRANSLATION AND TRANSCRIPTION

Subordinate Distinctions In addition to the above mentioned designations, master horizons are further characterised by specific properties such as distinctive colour or the ac

What is the autotrophic hypothesis on the origin of life? The autotrophic hypothesis on the origin of life asserts that the first living beings on earth were producers of thei

What is the role of platelet plug formation in hemostasis? What events occur during platelet plug formation? Describe the circumstances that may induce inappropriate platelet plug

What is osmotic pressure? Osmotic pressure is the pressure formed in an aqueous solution by a region of lower solute concentration upon a region of higher solute concentration

Describe Lifetime Risk Estimation ? Traditional statistical and epidemiological methods of estimating long-term risks do not accurately reflect population burden of disease. Th

What is the plant transpiration? What are the two major types of plant transpiration process? Which of them is more important in volume? The Plant Transpiration is the loss of

Which of the following statements least accurately explains our knowledge of how gene number relates to "organismal complexity"? A. Based on known gene numbers there appears to

Q. Describe about Collective or Universal consciousness? Neurochemicals and associated brain processes are simply channel selectors for various states of consciousness. All sta